10–11 Sept 2019
DoubleTree Hotel
US/Eastern timezone

Intrinsically disordered regions (IDRs) in proteins have emerged as a major research theme in modern biology, challenging the traditional protein structure-function paradigm. Our workshop aims at approaching the topic from an overarching macromolecular viewpoint. We suggest that IDRs and synthetic polymers, especially those with tunable degrees of internal interactions, such as electrostatic, hydrophobic, etc., share common research questions and have similar needs for experimental, computational and theory tools. More specifically, neutron scattering techniques have made key contributions to understanding polymer conformational dynamics and are poised to significantly contribute to the evolving area of functional disorder in proteins. The purpose of this workshop is to identify common ground between the research areas and identify potential synergies in experimental techniques and in approaches to analysis and interpretation of IDRs and polymers. We anticipate that the workshop discussions will be informative for defining future capability requirements for neutron scattering instrumentation, including considerations of spatial range and resolution, energy resolution, and demands on sample environments and real-time resolution in kinetic experiments.

Starts
Ends
US/Eastern
DoubleTree Hotel
Salon A
215 S Illinois Ave. Oak Ridge, TN 37830