16–17 Oct 2019
US/Eastern timezone

Agenda

The overall format is a two-day workshop consisting of talks in the morning (8:30 am - 12:00 pm) and afternoon (1:00 pm-5:30 pm).

There is no registration for this workshop.  All are welcome to attend.    

Functional Heterogeneities and Phase Separation in Biological Membranes:
Theory, Computations, and Experiment
October 16-17, 2019
Oak Ridge National Laboratory

Shull Wollan Center (ORNL Building 8630) - Room A202

Day 1   –   Wednesday, October 16th

8:00am-8:30am   –   Registration

8:30am-9:30am   –   Direct Imaging of Nanoscale Lipid Organization in Probe-Free Biomimetic Membranes   –   Fred Heberle, University of Tennessee

9:30am-10:30am   –   Coarse-Grained Modeling of Morphological Heterogeneities in Biomembranes   –   Mohamed Laradji, University of Memphis

10:30am-11:00   –   Break

11:00am-12:00pm   –   Membrane Protein Transport: Balancing Advection and Diffusion   –   Aurelia Honerkamp-Smith, Lehigh University

12:00pm-1:00pm   –   Break

1:00pm-2:00pm   –   The Biophysical Consequences of the Asymmetric Mammalian Lipidome   –   Ed Lyman, University of Delaware

2:00pm-3:00pm   –   Brief Calcium Influx through the Plasma Membrane Transiently Clusters PIP2 in the Inner Plasma Membrane Leaflet of Intact Cells   –   Arnd Pralle, University at Buffalo

3:00pm-3:30pm   –   Break

3:30pm-4:30pm   –   Modeling Membrane Heterogeneities at Small and Large Length Scales   –   Lutz Maibaum, University of Washington

4:30pm-5:30pm   –   Insights into Solvent-Microbial Stress in Biofuel Production from Small-Angle Scattering and Complementary Molecular Dynamics Simulations   –   Micholas Smith, ORNL/University of Tennessee

Day 2   –   Thursday, October 17th

8:30am-9:30am   –   Functional Roles for Lipid-Encoded Properties in Engineered Cell Membranes   –   Itay Budin, UC San Diego

9:30am-10:30am   –   All-Atom Modeling Nanometer-Scale Lateral Compositional Heterogeneity of the Liquid Ordered Phase Agrees with Small Angle Neutron Scattering Experiments   –   Alexander Sodt, National Institute of Health

10:30am-11:00am   –   Break

11:00am-12:00pm   –   Using 13C and 15N Isotope Tracers to Monitor Membrane Dynamics in C. elegans   –   Carissa Perez Olsen, Worcester Polytechnic Institute

12:00pm-1:00pm   –   Break

1:00pm-2:00pm   –   Modeling Lipid Composition Dynamics on the Surface of Membranes   –   Frank L. H. Brown, UC Santa Barbara

2:00pm-3:00pm   –   The Interplay Between Lipid Cross-Linking, Phase Separation, and Diffusion with Nanoscale Membrane Curvature   –   Christopher V. Kelly, Wayne State University

3:00pm-3:30pm   –   Break

3:30pm-4:30pm   –   Stimuli-Responsive Liposomes Through Modulation of Membrane Properties Using Synthetic Lipid Switches   –   Michael Best, University of Tennessee

4:30pm-5:30pm   –   Neutron vs. X-ray Scattering to Address Structures of Single Model Lipid Mono- and Bi-layers   –   Jaroslaw Majewski, NSF

5:30pm-6:00pm   –   Discussion/Concluding Remarks