11–14 Aug 2025
Crowne Plaza Knoxville
US/Eastern timezone

Deuteration of Molecules and Macromolecules

Not scheduled
20m
Crowne Plaza Knoxville

Crowne Plaza Knoxville

401 W Summit Hill Dr SW, Knoxville, TN 37902
Poster Only

Speakers

Honghai Zhang Qiu Zhang

Description

Small-angle neutron scattering (SANS) has become a very powerful technique to obtain structural information of polymers, functional organic materials and biomolecules. With this technique, different kinds of deuterated molecules are needed to obtain a high signal-to-noise ratio and selectively highlight the desired parts in complex system. In recent work, we synthesized several deuterated monomers, lignin, ionizable lipids and phosphatidylcholine for SANS studies. To shorten the synthetic period of deuterated molecules, we also established a deuteration platform for amines and amides, which are key precursors of many polymers, biomolecules and drug molecules. These works will enhance our deuteration capability and attract more users for neutron experiments

Topical Area Biology and life sciences

Author

Co-authors

Hugh O'Neill (Oak Ridge National Laboratory) Peter Bonnesen Qiu Zhang Wellington Leite (Oak Ridge National Laboratory)

Presentation materials

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