7-10 August 2016
Hilton Downtown Knoxville, TN
US/Eastern timezone

On behalf of the international advisory committee and the local organizing and program committee, we invite you to join us at the 5th International Symposium on Diffraction Structural Biology.

The aim of this symposium is to report on the latest discoveries in structural biology using X-ray, neutron, and electron diffraction, and complementary techniques such as small-angle scattering, nuclear magnetic resonance spectroscopy, electron microscopy, and advanced computational approaches. Scientific insights at the molecular level allow structure guided drug discovery and protein engineering for improved biocatalysis. This basic research is important for supporting applications in the pharmaceutical industry and for new, sustainable, and environmentally friendly approaches to the production of chemical reagents and biofuels. Discoveries in structural biology are accelerated by the availability of advanced research user facilities and new methods and technologies. In this symposium, we will cover the latest developments in electron, photon and neutron sources and associated methods and instrumentation. The symposium will include tours of the two advanced neutron scattering research facilities, the High Flux Isotope Reactor (HFIR) and the Spallation Neutron Source (SNS), and the TITAN supercomputer operated by Oak Ridge National Laboratory. Neutron scattering facilities are vital and unique tools for studying biological systems because the neutron's fundamental physical properties can provide information about biological systems that is unattainable by other means. Neutrons are most powerfully applied when combined with complementary experimental techniques that use photons and electrons. In addition, computer simulations using high performance computing enable prediction and interpretation of neutron scattering data from systems that are too complex for analytical theory.

Session topics include:


Drug Design

Enzyme Mechanism and Allostery

Macromolecular Complexes

Membranes and Membrane Proteins

New Instruments and Methods

Sources and Facilities

Our Sponsors:

Starts 7 Aug 2016 12:00
Ends 10 Aug 2016 18:00
Hilton Downtown Knoxville, TN
Cherokee Ballroom
501 W Church Avenue Knoxville, TN 37902